Actives for Lash & Brow Serums
Non-PG hair growth actives and cosmetic peptides for regulated lash & brow markets
For lash/brow serum brands navigating prostaglandin regulation and evaluating alternative active ingredients
Your Challenge. Our Answer.
We understand the specific problems you face — and we built solutions for each one.
The Problem
EU SCCS and Health Canada have flagged or restricted prostaglandin analogues in cosmetics, creating regulatory uncertainty for lash/brow serums
Mironova’s Answer
Mironova offers both prostaglandin analogs (for markets where permitted) and non-PG alternatives — so your brand can adapt to any regulatory environment
The Problem
Single-source prostaglandin supply creates business risk if that supplier faces quality or regulatory issues
Mironova’s Answer
Mironova manufactures multiple PG analogs in-house, providing supply diversification with consistent quality from one US facility
The Problem
Consumer awareness of prostaglandin side effects (periorbital fat loss, iris darkening) is driving demand for PG-free alternatives
Mironova’s Answer
Our non-PG hair growth actives (Kopyrrol Aqua, Kopexil Aqua) and cosmetic peptides offer alternative mechanisms without PG-associated concerns
Published Evidence
Key findings from peer-reviewed literature relevant to your application.
EU Regulatory Landscape
SCCS concludes that prostaglandin analogues MDN, isopropyl cloprostenate, and DDDE cannot be considered safe in cosmetic products for eyelash/eyebrow growth.
EU SCCS Opinion SCCS/1680/25
Canada PG Prohibition
Prostaglandins, their salts, derivatives and analogues are listed as prohibited in cosmetic products in Canada.
Health Canada Cosmetic Ingredient Hotlist
Non-PG Mechanism: Collagen Modulation
DPO (aminexil) modulates lysyl hydroxylase mRNA expression, targeting the collagen maturation pathway — a mechanistically distinct approach from prostaglandins.
Mahé et al., Skin Pharmacology 1996
Recommended Products
The specific products from our catalog that match your application.
Lash/Brow Serum Formulation Notes
- Diaminopyrimidine actives: 0.2–1.5% (w/w); cosmetic peptides: 1–50 ppm
- Water-soluble actives — no organic co-solvents needed for periorbital application
- Myristoyl lipopeptides pair well in multi-target lash serums (keratin + growth phase support)
- Compatible with common serum bases (HA, glycerin, panthenol)
- pH stability range: 4.5–7.0 for peptide-containing formulations
- Contact Mironova for prostaglandin analog availability in your market
Request Technical Data
Get product specifications, CoA samples, and pricing for your evaluation.
Discuss Your Formulation Needs
Our team can help navigate the PG regulatory landscape and recommend the right active strategy for your market and brand positioning.
Or call us at +1 (973) 244-0393
Related Resources
Technical data, product specifications, and application guidance.