A naturally occurring amino acid antioxidant with growing interest across supplement, food, and cosmetic applications.
L-Ergothioneine supply
Choose EGT-S synthesis for control from starting materials, or EGT-F Mironova-purified fermentation-derived EGT for lower ingredient cost with purification and documented residue testing.
EGT-S · US synthesis
$15,000 / kg
Base pricing in USD · MOQ 1 kg · Final quote required
Defined chemical synthesis, control from starting materials through release, and no fermentation production strain. Non-GMO. Recommended for synthesis control, programs requiring a non-GMO designation, and clinical supply.
Synthesized and released at Mironova, Fairfield, New Jersey.
Request a sample or quoteEGT-F · Purification and testing value
$10,000 / kg
Base pricing in USD · MOQ 3 kg · Final quote required
Fermentation economics. Mironova purification. Documented batch quality.
Fermentation-derived L-ergothioneine from imported material, extensively purified and recrystallized by Mironova in Fairfield, New Jersey. Every finished batch undergoes PicoGreen residual dsDNA analysis and USP microbial limits testing, including EGT matrix method suitability, before QA release.
Purified and finished in the USA from imported fermentation-derived L-ergothioneine.
Request a sample or quoteFermentation-derived EGT needs extensive downstream purification and residue verification. Mironova adds that work after importing the fermentation material, with purification, recrystallization, finishing, and release in Fairfield, New Jersey.
Imported fermentation-derived L-ergothioneine is quarantined and identity-verified at Fairfield, New Jersey. Mironova does not ferment.
Mironova extensively purifies and recrystallizes the imported material, then finishes and packages it in Fairfield, New Jersey.
PicoGreen residual dsDNA analysis and USP <61>/<62> microbial limits testing include method suitability in the EGT matrix. The release panel also includes endotoxin and host-cell-protein testing.
QA reviews finished-batch results against PS-EGT-F Rev. 4. Each batch CoA reports the measured residual dsDNA value and microbial results.
Every finished batch tested for residual dsDNA (PicoGreen) and USP microbial limits. EGT matrix method suitability is included before QA release. EGT-F also carries endotoxin and host-cell-protein testing. The quantitative dsDNA value is reported in ng/g on each batch CoA; high HPLC purity does not measure DNA or microbial content.
EGT-F is fermentation-derived, and the production microorganism may be a genetically modified strain. PicoGreen measures total residual dsDNA and is not sequence-specific, so it does not establish the absence of GM-derived DNA. Mironova makes no GMO residue-free, non-GMO, or non-GM-strain claim for EGT-F. Use EGT-S where a non-GMO designation is essential.
Finished-ingredient batch testing supports buyer qualification, including review for EU programs. Food and supplement suitability depends on the applicable novel-food authorization, production process, specifications, and intended use. A residual-DNA result alone does not establish EU market authorization or a non-GMO designation.
L-Ergothioneine (EGT) is a naturally occurring amino acid that functions as a cytoprotective antioxidant. Unlike many antioxidants, EGT accumulates in cells via a specific transporter (OCTN1), suggesting a distinct physiological role.
Found in mushrooms and certain bacteria, EGT has demonstrated notable stability and cellular retention. Researchers have proposed it may serve an important biological role given its dedicated transport mechanism.
Exceptional radical scavenging capacity with prolonged cellular retention.
Crosses blood-brain barrier; accumulates in neural tissue.
Scavenges reactive oxygen species in mitochondria and cytoplasm.
CAS Number
497-30-3
Formula
C9H15N3O2S
Molecular Weight
229.30 g/mol
Appearance
White to Off-White Powder
Purity (HPLC)
NLT 99.5%
Solubility
Water
Standard pack sizes: 1kg, 5kg, 25kg.
Custom specifications available.
Mironova Labs has secured multiple patents highlighting our advancements in ergothioneine research and applications.
Patent WO2024006568A1
Various salt forms of L-ergothioneine, including crystalline structures and preparation methods to enhance stability and bioavailability.
Patent US20160264530A1
Nα,Nα,Nα-Trialkyl histidine derivatives for EGT synthesis. A robust, scalable manufacturing approach from readily available starting materials.
Patent WO2019173159A1 (US 11,504,355 B2)
Compositions and methods in which ergothioneine maintains and increases intracellular vitamin C levels, enhancing cellular antioxidant defenses.
L-Ergothioneine's unique properties make it ideal for diverse industries and formulations.
Scientifically-validated, proprietary line of EGT-based solutions designed for cosmetic and beauty applications with enhanced stability and efficacy.
SKU: MNL-MC1
EGT on Non-Colloidal Microcrystalline Cellulose (MCC) - Ideal for anhydrous-based cosmetic applications.
Lipsticks • Foundations • Color Cosmetics • Solid Cleansers • Pencils
SKU: MNL-MC2
EGT on Colloidal Microcrystalline Cellulose (cMCC) - Ideal for aqueous-based cosmetic formulations.
Creams & Lotions • Serums • Facial Cleansers • Lash & Mascara Products
Co-developed with Barnet Products
Powerful Ascorbic Acid Booster Technology - Combines Magnesium Ascorbyl Phosphate (MAP) with EGT for enhanced cellular protection.
In cell-based studies, adding a small amount of EGT to MAP increased intracellular vitamin C by up to ~300% (threefold or more) under oxidative stress. In-vitro data per Mironova patent WO2019173159A1 (US 11,504,355 B2); not a human clinical result.
Contact our team to discuss formulation support, custom quantities, and technical documentation.
