Coupling
Reagents.
Advanced coupling reagents for efficient amide bond formation. From peptide synthesis to bioconjugation, our high-purity reagents support consistent, reproducible chemistry.
Full Catalog
Available Compounds
CDMT
3140-73-6
High-purity CDMT (2-chloro-4,6-dimethoxy-1,3,5-triazine) — the activated triazine precursor for in-situ DMTMM generation and direct amide bond formation in organic media.
DMTMM chloride (Cl⁻)
3945-69-5
High-purity DMTMM triazine-based coupling reagent for efficient amide bond formation in aqueous and organic media. Ideal for peptide synthesis, polysaccharid...
DMTMM tetrafluoroborate (BF₄⁻)
293311-03-2
High-purity tetrafluoroborate coupling reagent salts for peptide synthesis and organic chemistry. Cost-efficient alternative to hexafluorophosphate with...
DMTMM hexafluorophosphate (PF₆⁻)
1129971-87-4
High-purity hexafluorophosphate coupling reagent salts for peptide synthesis and organic transformations. Available as various counterion salts for...
Evaluate DMTMM for Your Application
Protocols, head-to-head comparisons vs EDC/NHS and HATU, application-specific salt recommendations, and troubleshooting guides — everything you need to run your first experiment.
Ready-to-Use Protocols
SPPS, aqueous amidation, lipidation, and on-DNA chemistry
Reagent Comparisons
DMTMM vs EDC/NHS, HATU, PyBOP with published data
Application Guide
Salt selection by workflow: Cl, BF₄, or PF₆
See How Teams Use These Products
Evaluation guides tailored to your industry — see which products fit your application, review key evidence, and request samples.
Why Choose Our Coupling Reagents
Engineered for Excellence
Exceptional Purity
≥99% purity by HPLC supports consistent coupling efficiency and helps minimize side reactions in your synthesis.
Versatile Applications
From peptide synthesis to surface functionalization, our reagents perform reliably across diverse applications.
Scalable Supply
Available from research quantities to kilo-scale production with the same exacting quality standards.
Need a Custom Coupling Reagent?
Our synthesis team can develop and manufacture custom coupling reagents to your exact specifications.